解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:INTRODUCTION:Eye diseases and visual impairment more commonly affect elderly adults, thus, the majority of ophthalmic cohort studies have focused on older adults. Cohort studies on the ocular health of younger adults, on the other hand, have been few. The Raine Study is a longitudinal study that has been following a co...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033440
更新日期:2020-03-25 00:00:00
abstract:CONTEXT AND OBJECTIVES:Neighbourhood effect research on obesity took off in the early 2000s and was composed of mostly cross-sectional observational studies interested in various characteristics of the built environment and the socioeconomic environment. To limit biases related to self-selection and life course exposur...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034690
更新日期:2020-03-25 00:00:00
abstract:OBJECTIVE:To describe the circumstances of the elderly with dementia and their caregivers' characteristics in order to examine factors related to activities of daily living (ADL) and household income to propose a long-term care policy for rural areas of Thailand. SETTING:A cross-sectional study at the household level ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032637
更新日期:2020-03-24 00:00:00
abstract:INTRODUCTION:Current pharmacological treatment options for hyperemesis gravidarum have been introduced based on scarce evidence and are often not sufficiently effective. Several case reports suggest that mirtazapine, an antidepressant, may be an effective treatment for hyperemesis gravidarum, but so far there are no co...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034712
更新日期:2020-03-24 00:00:00
abstract:OBJECTIVE:Lung cancer is increasingly recognised as a heterogeneous disease. Recent advances with targeted therapies for lung cancer with oncogenic mutations have greatly improved the prognosis for this subset of patients, yet little is known about their experiences. This study aimed to identify the needs and explore t...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032639
更新日期:2020-03-23 00:00:00
abstract:OBJECTIVE:To investigate the association between ambient air pollution and stroke morbidity in different subgroups and seasons. METHODS:We performed a time-series analysis based on generalised linear models to study the short-term exposure-response relationships between air pollution and stroke hospitalisations, and c...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032974
更新日期:2020-03-19 00:00:00
abstract:OBJECTIVES:There has been increased interest in screening for atrial fibrillation (AF) with commissioned pilot schemes, ongoing large clinical trials and the emergence of inexpensive consumer single-lead ECG devices that can be used to detect AF. This qualitative study aimed to explore patients' views and understanding...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033061
更新日期:2020-03-18 00:00:00
abstract:PURPOSE:To design a linked hospital database using administrative and clinical information to describe associations that predict infectious diseases outcomes, including long-term mortality. PARTICIPANTS:A retrospective cohort of Townsville Hospital inpatients discharged with an International Classification of Diseases...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034845
更新日期:2020-03-18 00:00:00
abstract:OBJECTIVES:Over the last 15 years, the prevalence of HIV in Haiti has stabilised to around 2.0%. However, key populations remain at higher risk of contracting HIV and other sexually transmitted infections (STIs). The prevalence of HIV is 12.9% among men having sex with men (MSM). There is limited information about the ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033976
更新日期:2020-03-16 00:00:00
abstract:INTRODUCTION:Mild obstructive sleep-disordered breathing (oSDB), characterised by habitual snoring without frequent apnoeas and hypopnoeas on polysomnography, is prevalent in children and commonly treated with adenotonsillectomy (AT). However, the absence of high-level evidence addressing the role of AT in improving he...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033889
更新日期:2020-03-15 00:00:00
abstract:OBJECTIVES:To determine whether a pre-existing smartphone app to teach mindfulness meditation is acceptable to women with chronic pelvic pain (CPP) and can be integrated into clinical practice within the National Health Service (NHS) CPP pathways, and to inform the design of a potential randomised clinical trial. DESI...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-030711
更新日期:2020-03-12 00:00:00
abstract:INTRODUCTION:Published in 2018, the 5C scale is psychometrically validated to assess five psychological antecedents of vaccination (confidence, complacency, constraints, calculation and collective responsibility). The original version offers a validated English and German scale to assess these determinants with a short...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034869
更新日期:2020-03-10 00:00:00
abstract:PURPOSE:In response to the need for more advanced and longitudinal data concerning chronic diseases, behavioural risk factors and social support systems in India, the SWADES (Social Well-being and Determinants of Health Study) was established. PARTICIPANTS:At baseline, 997 adults aged 30 years and over, living in the ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032803
更新日期:2020-03-09 00:00:00
abstract:OBJECTIVES:To perform the cross-cultural adaption of the Breast Cancer Awareness Measurement (BCAM) and to test its psychometric properties among Chinese women. DESIGN:This is a cross-sectional study. SETTINGS:This study was conducted in communities, schools and institutions in Changchun, Jilin Province, China. PART...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035911
更新日期:2020-03-09 00:00:00
abstract:INTRODUCTION:Tobacco causes kidney damage that can progress to chronic kidney disease. However, the diagnostic parameters used in clinics are not effective in identifying smokers at risk. Our first objective is to more effectively detect subclinical renal damage in smokers. In addition, we hypothesise that tobacco cons...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032918
更新日期:2020-03-08 00:00:00
abstract:INTRODUCTION:Severe behavioural problems (SBPs) are a common contributor to morbidity and reduced quality of life in children with intellectual disability (ID). Current medication treatment for SBP is associated with a high risk of side effects. Innovative and safe interventions are urgently needed. Anecdotal reports a...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034362
更新日期:2020-03-08 00:00:00
abstract:INTRODUCTION:Millions of women suffer from the consequences of endometriosis and uterine fibroids, with fibroids the cause for over 50% of hysterectomies in the USA, and direct costs for their treatment estimated at between US$4 and US$9 billion. Endometriosis commonly affects millions of women worldwide predominantly ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032220
更新日期:2020-03-04 00:00:00
abstract:INTRODUCTION:Musculoskeletal deformities and gait deviations are common features in ambulatory cerebral palsy (CP). Deformity correction through lower limb orthopaedic surgery is the standard form of care aimed at improving or preserving motor function. Current research on CP care does not always take into account indi...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034744
更新日期:2020-03-04 00:00:00
abstract:OBJECTIVES:To determine the availability of continuous positive airway pressure (CPAP) and to provide an overview of its use in neonatal units in government hospitals across India. SETTING:Cross-sectional cluster survey of a nationally representative sample of government hospitals from across India. PRIMARY OUTCOMES:...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031128
更新日期:2020-02-28 00:00:00
abstract:OBJECTIVES:Food insecurity is 'the limited or uncertain availability of nutritionally adequate, safe foods or inability to acquire foods in socially acceptable ways'. Majority of tuberculosis (TB) cases of resource-poor settings experience food insecurity, which impacts treatment adherence and outcomes. We aimed to det...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033798
更新日期:2020-02-28 00:00:00
abstract:INTRODUCTION:Limb fractures in children are common yet there are few trials that compare treatments for these injuries. There is significant heterogeneity in the outcomes reported in the paediatric orthopaedic literature, which limits the ability to compare study results and draw firm conclusions. The aim of the CORE-K...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-036224
更新日期:2020-02-28 00:00:00
abstract:OBJECTIVES:This article summarises all the available evidence on the impact of introducing blood-based point-of-care panel testing (POCT) in ambulatory care on patient outcomes and healthcare processes. DESIGN:Systematic review and meta-analysis of randomised-controlled trials and before-after studies. DATA SOURCES:O...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032132
更新日期:2020-02-27 00:00:00
abstract:OBJECTIVE:To compare the long-term economic impact of melanoma prevention by sun protection, with the corresponding impact of early detection of melanoma to decrease melanoma deaths. DESIGN:Cost-effectiveness analysis using Markov cohort model. Data were primarily from two population-based randomised controlled trials...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034388
更新日期:2020-02-26 00:00:00
abstract:INTRODUCTION:Trabeculotomy and combined trabeculotomy-trabeculectomy (CTT) are major surgical options for primary congenital glaucoma (PCG). However, it is unclear which of these two surgical procedures should be recommended as the optimum first-line treatment for PCG. This trial aims to determine whether the outcomes ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032957
更新日期:2020-02-25 00:00:00
abstract:INTRODUCTION:Falls are a concern for wheelchair users with spinal cord injury (SCI). Falls can negatively impact the physical and psychological well-being of fallers. To date, the perspectives of wheelchair users with lived experiences of SCI on the contributors to falls has been understudied. Information about factors...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034279
更新日期:2020-02-25 00:00:00
abstract:INTRODUCTION:Chronic musculoskeletal pain is a complex medical condition that can significantly impact quality of life. Patients with chronic pain demonstrate attentional biases towards pain-related information. The therapeutic benefits of modifying attentional biases by implicitly training attention away from pain-rel...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-030607
更新日期:2020-02-20 00:00:00
abstract:OBJECTIVES:Physical activity is widely recommended in the treatment and management of cystic fibrosis (CF). Despite the numerous physical and psychological benefits, many young people with CF are not achieving the recommended levels of physical activity. The aim of this systematic review was to identify and synthesise ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035261
更新日期:2020-02-20 00:00:00
abstract:OBJECTIVE:To systematically review the literature exploring the impact of isolation on hospitalised patients who are infectious: psychological and non-psychological outcomes. DESIGN:Systematic review with meta-analysis. DATA SOURCES:Embase, Medline and PsycINFO were searched from inception until December 2018. Refere...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-030371
更新日期:2020-02-18 00:00:00
abstract:OBJECTIVE:To estimate the costs and outcomes associated with treating non-asthmatic adults (nor suffering from other lung-disease) presenting to primary care with acute lower respiratory tract infection (ALRTI) with oral corticosteroids compared with placebo. DESIGN:Cost-consequence analysis alongside a randomised con...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033567
更新日期:2020-02-18 00:00:00
abstract:OBJECTIVE:To evaluate the incidence and management of local and systemic complications afflicting patients with de novo metastatic prostate cancer (mPCa) in Singapore. DESIGN:Retrospective analysis of a large prospective Uro-oncology registry of mPCa. SETTING:This study is carried out in a tertiary hospital in Singap...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034331
更新日期:2020-02-18 00:00:00
abstract:BACKGROUND:More than two decades of conflict and natural disasters in Somalia have resulted in one of the longest running humanitarian crises in the world. Nutrition data have been collected over the years despite challenges to inform programmatic action. This paper explores malnutrition and morbidity trends in Somalia...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033148
更新日期:2020-02-17 00:00:00
abstract:INTRODUCTION:Parkinson's disease is the second most common chronic neurodegenerative condition with bladder dysfunction affecting up to 71%. Symptoms affect quality of life and include urgency, frequency, hesitancy, nocturia and incontinence. Addressing urinary dysfunction is one of the top 10 priority research areas i...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034887
更新日期:2020-02-17 00:00:00
abstract:OBJECTIVE:We aimed to evaluate the safety, efficiency and preferred indication for laparoendoscopic single-site surgery (LESS) compared with conventional laparoscopic (CL) surgery for benign ovarian masses. DESIGN:A systemic review and cumulative meta-analysis were performed in line with the criteria of Grading of Rec...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032331
更新日期:2020-02-16 00:00:00
abstract:OBJECTIVE:To determine whether occupational exposure to silica dust causes an increased risk of developing Crohn's disease (CD) and ulcerative colitis (UC). DESIGN:Case-control study of CD (K50) and UC (K51) from 2007 through 2016. Controls were matched to cases (2:1) based on age, sex and county at the time of diagno...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034752
更新日期:2020-02-16 00:00:00
abstract:INTRODUCTION:There has been a growing awareness of the need for rigorously and transparent reported health research, to ensure the reproducibility of studies by future researchers. Health economic evaluations, the comparative analysis of alternative interventions in terms of their costs and consequences, have been prom...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034463
更新日期:2020-02-13 00:00:00
abstract:INTRODUCTION:Transition between health services is widely recognised as a problematic hurdle. Yet, the factors necessary for successful transition out of child and adolescent mental health services (CAMHS) as youth reach the service boundary at age 18 are poorly understood. Further, fragmentation and variability among ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-035744
更新日期:2020-02-12 00:00:00
abstract:OBJECTIVE:This study aimed to characterise rheumatic manifestations and autoantibodies in 432 patients diagnosed with infective endocarditis (IE) in Shanghai. DESIGN, SETTING AND PARTICIPANTS:A retrospective study was conducted in Ruijin Hospital from 1997 to 2017. The clinical and laboratory characteristics of a tota...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031512
更新日期:2020-02-12 00:00:00
abstract:OBJECTIVES:To promote gender diversity and equity in higher education, Athena Scientific Women's Academic Network (SWAN) supports and recognises higher education institutions (HEI) in advancing the careers of women through charter commitment, awards, training and advocacy since 2005. Most evaluation studies, however, a...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-032915
更新日期:2020-02-12 00:00:00
abstract:INTRODUCTION:High-flow nasal oxygen (HFNO) use in adults hospitalised with acute respiratory failure (ARF) is increasing. However, evidence to support widespread use of HFNO compared with non-invasive ventilation (NIV) and conventional oxygen therapy (COT) is unclear. This protocol describes the methods for a systemati...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034956
更新日期:2020-02-12 00:00:00
abstract:INTRODUCTION:Chemotherapy may cause infertility in young survivors of breast cancer. Various fertility preservation techniques increase the likelihood of survivors becoming genetic mothers. Disclosure of cancer diagnosis may impact decision making about fertility preservation. This protocol will develop and test the ef...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-031739
更新日期:2020-02-10 00:00:00